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Nucleophilic substitution reaction

Nucleophilic substitution reaction

LC2.5.2.1

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Description

In a nucleophilic substitution reaction in organic chemistry, one functional group is replaced (= substituted) by another in a reaction. In a nucleophilic substitution reaction, an anion or a Lewis base attacks.

In this experiment, the hydroxyl group of alcohols is replaced with a chloride. When carrying out the substitution reaction, the students recognise that the speed of the substitution depends on whether a primary, secondary or tertiary alcohol is present.

Components of equipment sets

1	667057 4	Test tube rack metal, 20 mm Ø
1	30945 4	Universal pencil
1	665997 4	Graduated pipette 10 ml
1	666003 4	Pipetting ball (Peleus ball)
1	6045682 4	Powder spatula, steel, 185 mm
3	6659541 8	Rubber bulb
3	6659531 4	Dropping pipette 150 mm x 7 mm Ø
1	602022 4	Beaker Boro 3.3, 100 ml, squat
1	664131 4	Beaker Boro 3.3, 400 ml, squat
3	6640421 4	Test tube Fiolax 16 mm x 160 mm
1	ADACB501 4	Compact scale 500 g : 0.1 g
1	610010 8	Laboratory safety goggles
1	667609 4	Safety gloves, nitrile rubber, size 8
1	6755110 4	Zinc chloride, dry, 250 g Danger H302 H314 H335 H410
1	6746750 4	Hydrochloric acid, conc., 25 %, 250 ml Danger H314 H335 H290
1	6711010 4	1-Butanol, 1 l Danger H226 H302 H318 H315 H335 H336
1	6711210 4	2-Butanol, 1 l Warning H226 H319 H335 H336
1	6711300 4	Tertiary butanol, 100 ml Danger H225 H332 H319 H335

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Nucleophilic substitution reaction

Description

Components of equipment sets

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